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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제2호
- 발행연도
- 2018.1
- 수록면
- 129 - 135 (7page)
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초록· 키워드
오류제보하기
Autism spectrum disorder (ASD) is a series of neurodevelopmental disorder with a large genetic component. However, the pathogenic genes and molecular mechanisms of ASD have not been clearly defined. Recent technological advancements, such as next-generation sequencing, have led to the identification of certain loci that is responsible for the pathophysiology of ASD. Three functional pathways, such as chromatin remodeling, Wnt signaling and mitochondrial dysfunction are potentially involved in ASD. In this review, we will focus on recent studies of the involvement of Wnt signaling pathway components in ASD pathophysiology and related drugs used in ASD treatment.
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참고문헌 (43)
참고문헌 신청
American Psychiatric Association / 2013 / American Psychiatric Association. the Diagnostic and Statistical Manual of Mental Disorders 5th edition: DSM-5 / American Psychiatric Publishing
Sadock BJ / 2015 / Kaplan and Sadock's synopsis of psychiatry: behavioral science/clinical psychiatry. 11th ed. / Wolters Kluwer
Caracci MO / 2016 / Synaptic $Wnt/GSK3{\beta}$ signaling hub in autism / Neural Plast 2016:9603751
Mulligan KA / 2017 / Neurodevelopmental perspectives on Wnt signaling in psychiatry / Mol Neuropsychiatry 2:219~246
Loh KM / 2016 / Generating cellular diversity and spatial form: Wnt signaling and the evolution of multicellular animals / Dev Cell 38:643~655
Sadock BJ / 2015 / Kaplan and Sadock's synopsis of psychiatry: behavioral science/clinical psychiatry. 11th ed. / Wolters Kluwer
Caracci MO / 2016 / Synaptic
Mulligan KA / 2017 / Neurodevelopmental perspectives on Wnt signaling in psychiatry / Mol Neuropsychiatry 2:219~246
Loh KM / 2016 / Generating cellular diversity and spatial form: Wnt signaling and the evolution of multicellular animals / Dev Cell 38:643~655
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