Pitfalls in the 2017 TNM Classification of Thyroid Carcinoma

Gianlorenzo Dionigi; Antonio Ieni; Francesco Ferrau; Hui Sun; Salvatore Cannavo; Giovanni Tuccari

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자료유형: 학술저널

저자정보: Gianlorenzo Dionigi Antonio Ieni Francesco Ferrau Hui Sun Salvatore Cannavo Giovanni Tuccari

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제18권 제2호

발행연도: 2018.1

수록면: 98 - 109 (12page)

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The objective of this article is to detail the 2017 tumor-node-metastasis (TNM) staging criteria for thyroid cancer. The literature presents only few contributions, with controversial results, about comparison between previous and the new TNM systems. The 2017 TNM classification categorizes either thyroid carcinomas only limited to the gland either carcinomas macroscopically infiltrating into defined anatomical structures. The “minimal extrathyroid spread” into the perithyroidal adipose tissue no longer appears as a classification parameter in the new TNM. In the present paper is discussed for the pT categories pT1a, pT1b, pT2, and pT3a. In detail, the T-categories pT1a, pT1b, pT2, and pT3a are each subdivided into true thyroid-restricted carcinomas (pT1a1, pT1b1, pT2a1, and pT3a1) and “minimal extrathyroid proliferation” carcinomas (pT1a2, pT1b2, pT2b, and pT3a2). As a basis, a strict definition of the “minimal extrathyroid propagation” of thyroid carcinomas is essential. Although the suggestion made with the additional substrate characterization makes the work of the pathologist more intricate in daily use, standardized fundamentals for demonstrating or excluding the prognostic and therapeutic relevance concerning a “minimal extrathyroid extension” in thyroid carcinoma appear to be necessary.

참고문헌 (44)

참고문헌 신청

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