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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 692 - 702 (11page)
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초록· 키워드
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Streptococcus mutans causes oral diseases, including tooth decay, by producing a biofilm called plaque. Therefore, inhibition of biofilm formation is essential for maintaining oral health. Plants produce a variety of secondary metabolites, which act as starting sources for the discovery of new bioactive chemicals that inhibit biofilm formation of S. mutans. Previous studies have reported on chemicals with antibiotic activity for the inhibition of biofilm formation by S. mutans. In this study, nine plant extracts from Melonis Pedicellus, Agastachis Herba, Mori Cortex Radicis, Diospyros kaki leaves, Agrimoniae Herba, Polygoni Multiflori Radix, Lycopi Herba, Elsholtziae Herba, and Schizonepetae Spica were screened for the inhibition of biofilm formation from a plant extract library. The water-soluble compounds of the extracts did not affect cell growth but selectively inhibited biofilm formation. These results suggest that the selected plant extracts constitute novel biofilm formation inhibitors, with a novel biological mechanism, for improving oral hygiene.
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참고문헌 (62)
참고문헌 신청
Ahn, S.J. / 2008 / Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva / Infection and Immunity 76(9):4259~4268
Arakawa, H. / 2014 / Antibacterial activities of persimmon extracts relate with their hydrogen peroxide concentration / Biological and Pharmaceutical Bulletin 37(7):1119~1123
Beck, J. / 1996 / Periodontal disease and cardiovascular disease / Journal of Periodontology 67(Suppl 10S):1123~1137
Berbari, E.F. / 1997 / Infective endocarditis due to unusual or fastidious microorganisms / Mayo Clinic Proceedings 72(6):532~542
Bowen, W.H. / 2011 / Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms / Caries Research 45(1):69~86
Arakawa, H. / 2014 / Antibacterial activities of persimmon extracts relate with their hydrogen peroxide concentration / Biological and Pharmaceutical Bulletin 37(7):1119~1123
Beck, J. / 1996 / Periodontal disease and cardiovascular disease / Journal of Periodontology 67(Suppl 10S):1123~1137
Berbari, E.F. / 1997 / Infective endocarditis due to unusual or fastidious microorganisms / Mayo Clinic Proceedings 72(6):532~542
Bowen, W.H. / 2011 / Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms / Caries Research 45(1):69~86
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