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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 1 - 12 (12page)
- DOI
- 10.1186/s42649-021-00059-6
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초록· 키워드
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Intravital video microscopy permits the observation of microcirculatory blood flow. This often requires fluorescent probes to visualize structures and dynamic processes that cannot be observed with conventional bright-field microscopy. Conventional light microscopes do not allow for simultaneous bright-field and fluorescent imaging. Moreover, in conventional microscopes, only one type of fluorescent label can be observed. This study introduces multispectral intravital video microscopy, which combines bright-field and fluorescence microscopy in a standard light microscope. The technique enables simultaneous real-time observation of fluorescently-labeled structures in relation to their direct physical surroundings. The advancement provides context for the orientation, movement, and function of labeled structures in the microcirculation.
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등록된 정보가 없습니다.
참고문헌 (45)
참고문헌 신청
BARAA K. AL-KHAZRAJI / 2012 / A Simple “Streak Length Method” for Quantifying and Characterizing Red Blood Cell Velocity Profiles and Blood Flow in Rat Skeletal Muscle Arterioles / Microcirculation 19(4):327~335
R. Alon / 2002 / From rolling to arrest on blood vessels : leukocyte tap dancing on endothelial integrin ligands and chemokines at sub-second contacts / Semin. Immunol 14:93
Evelyne Beerling / 2016 / Intravital characterization of tumor cell migration in pancreatic cancer / IntraVital 5(3):e1261773
E. Beerling / 2011 / Intravital microscopy : new insights into metastasis of tumors / J. Cell Sci 124:299
R. Bordy / 2018 / Microvascular endothelial dysfunction in rheumatoid arthritis / Nat. Rev. Rheumatol 14:404
R. Alon / 2002 / From rolling to arrest on blood vessels : leukocyte tap dancing on endothelial integrin ligands and chemokines at sub-second contacts / Semin. Immunol 14:93
Evelyne Beerling / 2016 / Intravital characterization of tumor cell migration in pancreatic cancer / IntraVital 5(3):e1261773
E. Beerling / 2011 / Intravital microscopy : new insights into metastasis of tumors / J. Cell Sci 124:299
R. Bordy / 2018 / Microvascular endothelial dysfunction in rheumatoid arthritis / Nat. Rev. Rheumatol 14:404
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