한국 여성에서 신체질량지수와 유방암 발생과의 관련성에 대한 연구

강현석; 한재홍; 김종진; 이한별; 신희철; 한원식; 노동영; 문형곤

doi:https://doi.org/10.14449/jbd.2016.4.2.64

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자료유형: 학술저널

저자정보: 강현석 (서울대학교) 한재홍 (서울대학교 의과대학 외과학교실) 김종진 (서울특별시보라매병원) 이한별 (서울대학교) 신희철 (중앙대학교) 한원식 (서울대학교) 노동영 (서울대학교) 문형곤 (서울대학교)

저널정보: 한국유방암학회 Journal of Breast Disease Journal of Breast Disease 제4권 제2호

발행연도: 2016.12

수록면: 64 - 69 (6page)

DOI: https://doi.org/10.14449/jbd.2016.4.2.64

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Purpose: Obesity in women has been shown to have correlation with breast cancer incidence. The proportion of Korean women who are obese has increased recently. However, there is no large-scale study evaluating the relationship between obesity and breast cancer incidence in Korea. In this study, we tried to identify the relationship between obesity and breast cancer incidence in Korean women by using body mass index (BMI) Methods: A retrospective analysis was performed using single-center data of 28,631 patients screened with breast ultrasonography or mammography between January 2009 to December 2013 in Seoul National University Hospital Healthcare System Gangnam Center. Their clinical characteristics were evaluated. The correlations between breast cancer incidence with BMI and other factors were analyzed using univariate and multivariate logistic regression models. Results: A total of 28,631 patients were enrolled; 67 patients were diagnosed with breast cancer. Among patients without breast cancer, the proportion of patients with BMI under 23 was 68.1%, whereas it was 56.7% among patients with breast cancer (p=0.036). In univariate analysis, patients with a BMI over 25 had an odds ratio of 2.09 for breast cancer compared with those with a BMI under 23 (p=0.012). In addition, patients with a waist circumference over 85 cm had an odds ratio of 1.69 for breast cancer compared with the others (p=0.042). In multivariate analysis, BMI also had significant correlation with breast cancer incidence (odds ratio=1.87, p=0.035). Conclusion: An increase in BMI has positive correlation with breast cancer incidence in Korean women. However, a multi-centered prospective study is needed for further evaluation.

#Body mass index #Breast neoplasms #Incidence #Korea

참고문헌 (14)

참고문헌 신청

Worldwide cancer statistics / Cancer Research UK

Ministry of Health and Welfare / 2015 / Statistical Yearbook 2015

Gathirua-Mwangi WG / 2015 / Adult BMI change and risk of breast cancer: National Health and Nutrition Examination Survey (NHANES) 2005-2010 / Breast Cancer 22:648~656

Keinan-Boker L / 2016 / Measured adolescent body mass index and adult breast cancer in a cohort of 951,480 women / Breast Cancer Res Treat 158:157~167

Arnold M / 2016 / Overweight duration in older adults and cancer risk: a study of cohorts in Europe and the United States / Eur J Epidemiol 31:893~904

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