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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.2
- 수록면
- 71 - 77 (7page)
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Cancers are one of the most dreaded diseases in human historyand have been targeted by numerous trials including surgery,chemotherapy, radiation therapy, and anti-cancer drugs. Adultstem cells (ASCs), which can regenerate tissues and repairdamage, have emerged as leading therapeutic candidates dueto their homing ability toward tumor foci. Stem cells can preciselytarget malicious tumors, thereby minimizing the toxicityof normal cells and unfavorable side effects. ASCs, such asmesenchymal stem cells (MSCs), neural stem cells (NSCs), andhematopoietic stem cells (HSCs), are powerful tools for deliveringtherapeutic agents to various primary and metastatic cancers.
Engineered ASCs act as a bridge between the tumor sites andtumoricidal reagents, producing therapeutic substances suchas exosomes, viruses, and anti-cancer proteins encoded by severalsuicide genes. This review focuses on various anti-cancertherapies implemented via ASCs and summarizes the recenttreatment progress and shortcomings.
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